Sculptra® Aesthetic (injectable poly-L-lactic acid) is used as a single regimen for the correction of shallow to deep nasolabial fold contour deficiencies and other facial wrinkles in which deep dermal grid pattern (cross-hatch) injection technique is appropriate. Traditional collagen creams purport to deliver collagen that is absorbed by the skin. However, collagen molecules are too large to penetrate the dermis. So, in actuality, most of these treatments include vitamins and hold moisture, making them suitable moisturizers that can briefly improve skin’s appearance. Collagen dietary supplements are meant to facilitate the production of collagen within the body. However, collagen is a protein that, when ingested, is broken down by the digestive system. Results for these types of treatments are inconclusive. Toxins work by temporarily weakening muscles, typically in the forehead, to minimize frown lines. Results appear within a couple days and can last up to a couple months.